Advanced malignant tumors, including non-small cell lung cancer, colorectal cancer, and head-and-neck cancers
Conditions
Interventions
Gold Standard:Histopathological diagnosis or clinical follow-up findings will serve as the reference standard.
Index test:[68Ga]Ga-FL-261[111ln]In-FL-261 radionuclide imaging
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.The subject, or his/her legally authorized representative, is able to sign the informed consent form. 2. The subject agrees to comply with study procedures and to participate in the entire research process. 3. Adult patients (>=18 years of age), of any sex. 4. Patients with clinically suspected or confirmed tumors such as non-small cell lung cancer, colorectal cancer, or head-and-neck cancers, supported by evidence including, but not limited to, serum tumor markers, ultrasound, CT, MRI, or histopathological examination. 5. Patients with generally good overall physical condition. 6. Willingness to permit the use of existing tissue specimens.
Exclusion criteria
Exclusion criteria: 1. Patients or their legally authorized representatives who are unable or unwilling to sign the informed consent form. 2. Inability to comply with or complete the full study procedures. 3. Presence of acute systemic illness or significant electrolyte imbalance. 4. Pregnant or breastfeeding women. 5. Any other condition that, in the opinion of the investigator, makes the subject unsuitable for participation, such as patients with a known intolerance or hypersensitivity to c-MET–targeting agents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax; | — |
Countries
China
Contacts
Public ContactXiaoli Lan
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed