Geriatric Depression
Conditions
Interventions
A1:Routine parameters group of transcranial magnetic stimulation :The left dorsolateral prefrontal cortex (DLPFC), stimulated at 80% of the patients motor threshold, with a stimulation frequency of 10
A2:iTBS stimulation group:iTBS stimulation parameters: stimulation frequency of 3Hz, stimulation intensity at 120% of motor threshold, five sessions per week, each lasting 3 minutes, for a total of fo
A3:Sham - stimulation Group of Transcranial Magnetic Stimulation:Rotate the stimulating magnet 180° in relation to the scalp, keeping all other treatment parameters consistent with the A1 group.
B1:Vagus nerve stimulation intervention group:Psychiatrists trained the physicians responsible for this study. After disinfecting the ear area with alcohol, the physician placed the two ear clips of t
B2:Vagus nerve sham stimulation group:A pseudo-stimulation group was subjected to microcurrent stimulation without ta
Sponsors
Suzhou Guangji Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age: 60 to 85 years old; 2. After diagnosis by a professional physician, it meets the above-mentioned pathological diagnosis criteria for depression; 3. Have not received any treatment recently and suspend other treatment plans when receiving this treatment; 4. Be able to cooperate with all the steps of the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Subjects who do not meet the diagnostic criteria and inclusion criteria; 2. Taking other psychiatric medications; 3. Age beyond the inclusion range; 4. Rule out severe heart, lung, kidney and liver diseases, bleeding tendencies and functional system changes; 5. Exclude the presence of other mental disorders; 6. Subjects currently participating in other clinical trials; 7. Subjects who do not cooperate with the trial and do not sign the informed consent form; 8. Fear of the test method, obvious boundary effect of oral drugs, and severe allergy.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Assessment of cognitiion; | — |
Primary
| Measure | Time frame |
|---|---|
| Depressive assessment;Assessment of Anxiety Symptoms; | — |
Countries
China
Contacts
Public ContactYang Xuna
Suzhou Guangji Hospital
Outcome results
None listed