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Efficacy of Micro-osteoperforation Adjunctive to Miniscrew-Assisted Rapid Palatal Expansion: A Randomized Controlled Trial

Efficacy of Micro-osteoperforation Adjunctive to Miniscrew-Assisted Rapid Palatal Expansion: A Randomized Controlled Trial - Efficacy of MOP Adjunctive to MARPE: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113858
Enrollment
Unknown
Registered
2025-12-04
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maxillary transverse deficiency

Interventions

Group MARPE:Mini-screw Assisted Rapid Palatal Expansion (MARPE)
Group MOP+MARPE:Mini-screw Assisted Rapid Palatal Expansion (MARPE)+Micro-osteoperforation (MOP)

Sponsors

School & Hospital of Stomatology, Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with maxillary transverse deficiency by both the Pennsylvania transverse analysis and the Yonsei transverse analysis; 2. Cervical vertebral maturation (CVM) stage >= 5 according to the CVM method; 3. Treatment plan includes miniscrew-assisted rapid palatal expansion (MARPE); 4. No other orthodontic interventions during the expansion phase (e.g., facemask protraction); 5. Good oral hygiene; 6. Non-smokers.

Exclusion criteria

Exclusion criteria: 1. Cleft lip and/or palate or other craniofacial anomalies; 2. Previous orthodontic treatment and/or orthognathic surgery; 3. Uncontrolled gingivitis, periodontitis, gingival recession, or alveolar bone loss; 4. Missing or impacted first permanent molars; 5. Metabolic bone disease or other systemic disorders; 6. Inability or unwillingness to cooperate with MARPE; 7. Refusal to participate in the trial.

Design outcomes

Primary

MeasureTime frame
Midpalatal suture separation;Interdental distance change;Basal bone width change;

Secondary

MeasureTime frame
Nasal cavity width change;Craniofacial landmark changes;Anterior-posterior changes in the frontozygomatic angle (FZA), frontoalveolar angle (FAA), and frontodental angle (FDA);Airway change(minimum cross-sectional area);Patient-reported pain;

Countries

China

Contacts

Public ContactZhijian, Liu

School & Hospital of Stomatology, Wuhan University

liuzhijian@whu.edu.cn+86 27 8768 6290

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026