Mycoplasma pneumoniae pneumonia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) Meeting the indications for bronchoalveolar lavage, performed in accordance with the "2018 Chinese Pediatric Flexible Bronchoscopy Guidelines" expert consensus. (2) Positive MP DNA in the bronchoalveolar lavage fluid of children with MPP. (3) Detection of MP sequences in the bronchoalveolar lavage fluid of children with MPP through tNGS (transcriptional next-generation sequencing). (4) Positive MP IgM antibody in the blood of children with MPP. Meeting any one of the three criteria (2), (3), or (4), in addition to criterion (1), is sufficient for inclusion in the study.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) Patients with contraindications to bronchoalveolar lavage such as heart failure, severe arrhythmias, severe pulmonary insufficiency, and acute respiratory failure. (2) Patients with comorbidities involving the hematologic system, rheumatic autoimmune diseases, or other systemic diseases that may interfere with diagnosis and treatment. (3) Patients who cannot tolerate bronchoscopy procedures and discontinue treatment. (4) Patients allergic to medications used during bronchoscopy, such as anesthetics. (5) Patients who transfer hospitals or discontinue treatment mid-way through their hospital stay, or those with incomplete clinical data. (6) Patients participating in other research studies simultaneously with this study. (7) Patients who initially agree but later refuse to provide samples or refuse cooperation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genome sequencing;Drug sensitivity test results; | — |
Countries
China
Contacts
The First Hospital of Jilin University