Cesarean delivery
Conditions
Interventions
Paracetamol Group:Infusion of Paracetamol and Mannitol Injection 50ml
Control Group:Infusion of normal saline 50ml
Sponsors
Hangzhou Women's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Women aged 18 or older; 2.ASA grade II; 3.Elective cesarean section under combined spinal-epidural anesthesia; 4.Body Mass Index (BMI) ranging from 18 to 30 kg/m^2; 5.Signed informed consent form, willing to accept the experimental method and voluntarily participate as a subject;
Exclusion criteria
Exclusion criteria: 1.Emergency surgery; 2.Those with contraindications to combined spinal-epidural anesthesia; 3.Those with abnormal coagulation or hematopoietic function; 4.Liver diseases, such as acute hepatitis, liver failure, liver cirrhosis, etc. 5.Kidney diseases, such as acute renal failure, chronic renal insufficiency, etc. 6.Severe obstetric complications, such as uterine rupture, umbilical cord prolapse, gestational hypertension, preeclampsia and eclampsia; 7.Those who do not agree to participate or are currently participating in other drug trial studies;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of visceral traction pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative pain score;Apgar scores of newborns at 1 minute and 5 minutes;Incidence of rescue analgesia;Incidence of adverse events;Postoperative pain score; | — |
Countries
China
Contacts
Public ContactZhou Zhenfeng
Hangzhou Women's Hospital
Outcome results
None listed