Skip to content

Analysis of the Safety and Efficacy of Salbutamol on Sputum Induced by Hypertonic Saline

Analysis of the Safety and Efficacy of Salbutamol on Sputum Induced by Hypertonic Saline

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113772
Enrollment
Unknown
Registered
2025-12-03
Start date
2025-12-03
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertonic saline-induced sputum

Interventions

Research group:Received salbutamol 2 sprays after inducing sputum with hypertonic saline solution
Control group:Do not receive salbutamol 2 sprays after inducing sputum with hypertonic saline solution

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Clear consciousness and normal comprehension ability. 2.Subjects who have clinical indications for inducing sputum with hypertonic saline and are able to complete the entire process of inducing sputum with hypertonic saline. 3.I am willing to participate and sign the informed consent form. 4.The absolute improvement rate of FEV1 in lung function is = 70%, and the pulse, respiration, and blood oxygen saturation are normal.

Exclusion criteria

Exclusion criteria: 1.I am unwilling to participate. 2.The absolute improvement rate of FEV1 in lung function is less than 70%, and the pulse, respiration, and oxygen saturation are lower than normal values. 3.Vague meaning, understanding disabilities, intellectual disabilities, and those without expressive ability.

Design outcomes

Primary

MeasureTime frame
FEV1 absolute value improvement rate;

Secondary

MeasureTime frame
Oxygen saturation;Vital signs;Dyspnea and Cough VAS Score;

Countries

China

Contacts

Public ContactJingqing Zhou

Shanghai General Hospital

zhoujingqing@hotmail.com+86 21 63240090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026