defect of dentition
Conditions
Interventions
Control group:The control group will receive soft?tissue augmentation after tooth extraction using an autogenous palatal soft?tissue graft
Test group:Soft?tissue augmentation after tooth extraction will be performed using the Mucograft collagen matrix
Sponsors
Beijing Stomatological Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients requiring extraction of a single maxillary anterior tooth due to caries, endodontic complications, or trauma, who elect implant-supported restoration, with natural teeth present on both adjacent sides. 2.Age 18–65 years, both sexes eligible. 3:.Good oral hygiene, with a Plaque Index < 2 and bleeding on probing sites < 20%.
Exclusion criteria
Exclusion criteria: 1. Immediate probing/CBCT assessment prior to or following extraction confirms integrity of labial, palatal (lingual) and adjacent bone plates, with a minimum 2mm labial bone plate thickness. Candidates meeting clinical and radiographic criteria for immediate implant placement. 2. Presence of active or uncontrolled periodontal disease (PD >=4 mm), or acute infection at the target site; 3. Smoking habit (>10 cigarettes/day); 4. Surgical contraindications, history of head and neck radiotherapy, uncontrolled systemic diseases (e.g., diabetes mellitus), systemic conditions or medications affecting soft/hard tissue healing (e.g., bisphosphonate use); 5. Pregnant or lactating women; 6. Individuals with mental or intellectual disabilities; 7. History of allergic reactions to porcine or other animal-derived collagen/gelatin/blood products; 8. Religious prohibitions (e.g., Islam, Judaism) against porcine-derived materials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in alveolar bone dimensions and external soft?tissue contour; | — |
Secondary
| Measure | Time frame |
|---|---|
| Esthetic outcomes; | — |
Countries
China
Contacts
Public ContactZhenhua Gao
Beijing Stomatological Hospital, Capital Medical University
Outcome results
None listed