Severe pneumonia in children
Conditions
Interventions
Crossover Group 1:On the morning of Day 1, receive one session of traditional chest percussion and suctioning
on the afternoon of Day 1, receive one session of rehabilitation therapist-assisted sputum clearance
on the morning of the next day, receive another session of rehabilitation therapist-assisted sputum clearance.
Crossover Group 2:On the morning of Day 1, receive one session of rehabilitation therapist-assisted sputum clearance
on the afternoon of Day 1, receive one session of traditional chest percussion and suctioning
on the morning of the next day, receive another session of traditional chest percussion and suctioning.
Sponsors
Shengjing Hospital Affiliated to China Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 14 Years
Inclusion criteria
Inclusion criteria: 1. age 90%, positive end-expiratory pressure (PEEP) = 3 days and length of hospital stay >= 5 days as assessed by the attending physician; 7. informed consent from patient’s family members.
Exclusion criteria
Exclusion criteria: 1. receiving mechanical ventilation before ICU admission; 2. use of muscle relaxants during mechanical ventilation; 3. after cardiopulmonary resuscitation; 4. need for extracorporeal life support; 5. for children with severe acute respiratory distress syndrome, intervention should be implemented only when permitted by dynamic assessment of the attending physician; otherwise, exclusion applies; 6. presence of life-threatening organ failure such as liver or kidney failure requiring extracorporeal circulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory mechanics parameters of (pediatric patients) before intervention and at 1 min, 5 min, 15 min, and 30 min after intervention: ventilation mode, endotracheal tube inner diameter (cm), intubation depth (cm), airway resistance (Paw), dynamic lung compliance (Cydn), airway occlusion pressure (P0.1), P-V loop, tidal volume (Vt), total positive end-expiratory pressure (PEEPtot), peak airway pressure (Ppeak), plateau pressure (Pplat), intrinsic PEEP (PEEPi), and driving pressure (Pdriv =;Blood gas analysis parameters before and after intervention: arterial partial pressure of oxygen (PaO?), arterial partial pressure of carbon dioxide (PaCO?).;Sputum viscosity and sputum volume after expectoration.;Other indicators: duration of mechanical ventilation (h), PICU length of stay and total hospital length of stay (d), APACHE? score, CPIS score, PELOD-2 score.; | — |
Countries
China
Contacts
Public ContactXu Wei Duan Xiaoyuan
Shengjing Hospital Affiliated to China Medical University
Outcome results
None listed