Preeclampsia
Conditions
Interventions
Normal Control Group:None
Sponsors
Affiliated hangzhou first people's hospital, zhejiang university school of medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.Preeclampsia Group: Pregnant women aged 18–45 years. Meeting the International Federation of Gynecology and Obstetrics (FIGO) diagnostic criteria for preeclampsia. Single gestation. Voluntarily signed informed consent. 2.Normal Control Group: Pregnant women aged 18–45 years. Healthy pregnant women without gestational hypertension, proteinuria, or other severe pregnancy complications. Single-fetus pregnancies with full-term delivery. Voluntarily signed informed consent forms.
Exclusion criteria
Exclusion criteria: 1.Preeclampsia Group: Comorbidities with other severe pregnancy complications (e.g., HELLP syndrome, placental abruption). Comorbidities with chronic hypertension, diabetes, autoimmune diseases, or severe infections. Multiple pregnancies or fetal congenital anomalies. Recent use of immunosuppressive agents or anti-inflammatory drugs. 2.Normal control group: History of gestational hypertension, preeclampsia, or other pregnancy complications. Concurrent chronic conditions (e.g., hypertension, diabetes, autoimmune diseases). Multiple pregnancies or fetal abnormalities. Recent use of medications that may affect immune function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TTC4 and HSP70 Expression Levels in Placenta; | — |
Countries
China
Contacts
Public ContactHua Xue
Affiliated hangzhou first people's hospital, zhejiang university school of medicine
Outcome results
None listed