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Study on the correlation between elderly patients with coronary heart disease and frailty and the improvement of frailty by short-term nutritional intervention

Study on the correlation between elderly patients with coronary heart disease and frailty and the improvement of frailty by short-term nutritional intervention

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113759
Enrollment
Unknown
Registered
2025-12-03
Start date
2024-08-31
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Study on frailty in elderly patients with coronary heart disease

Interventions

Control group:Standard coronary artery disease treatment
Test group:Nutritional consultation and dietary guidance

Sponsors

Second Xiangya Hospital of CSU
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 60 years; 2. Meeting the diagnosis of coronary heart disease in the 2019 ESC Guidelines for Chronic Coronary Syndromes; ACS includes unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI) and ST-segment elevation myocardial infarction (STEMI). CCS includes: (1) patients with suspected coronary heart disease, accompanied by stable angina symptoms and/or dyspnea; (2) patients with new heart failure (HF) or left ventricular dysfunction, suspected of coronary heart disease; (3) asymptomatic and symptomatic patients with stable symptoms within 1 year after ACS, or patients who have recently undergone revascularization; (4) symptomatic or asymptomatic patients who have been diagnosed for the first time or revascularization for more than 1 year; (5) patients with angina and suspected vasospasm or microvascular disease; (6) asymptomatic patients found to have coronary heart disease through screening; 3. Those who can fully communicate and understand this study and provide informed consent; 4. Patients with Fried frailty phenotype were assessed as those in the pre-frail or frail stage.

Exclusion criteria

Exclusion criteria: 1.Patients with concurrent malignant tumors; 2.Patients with severe primary diseases such as liver/renal insufficiency who require a protein-restricted diet; 3.In the acute stage of heart failure or acute exacerbation of chronic heart failure; 4.Those who are unable to cooperate or complete the experiment; 5.Use of any dietary supplements within 3 months before screening.

Design outcomes

Primary

MeasureTime frame
Grip strength;Short distance pace;

Secondary

MeasureTime frame
Kidney Function Tests;Complete Blood Count;Liver Function Tests;

Countries

China

Contacts

Public ContactXu Danyan

Second Xiangya Hospital of CSU

xudanyan02@csu.edu.cn+86 13974874636

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026