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Monitor the effect of furosemide intravenous injection on circulation volume by pulse pressure variability during transurethral prostate surgery

Study on the protection of insufficient circulation volume caused by furosemide intravenous injection in monitoring of pulse pressure variability/stroke volume variability during transurethral prostate surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113748
Enrollment
Unknown
Registered
2025-12-02
Start date
2025-06-24
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign prostatic hyperplasia

Interventions

Control group :Saline 1ml iv
Furosemide group:Furosemide 0.2mg/Kg iV

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age: 50-85 years old. 2. ASA physical status: I-III. 3. Operation time: expected 90 minutes or more. 4. Transurethral plasmakentic vaporization of prostate electricity cut undergoing elective surgery patients. 5. Patients with spinal canal anesthesia in patients with contraindications or require general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Body mass index (BMI) >30kg/m^2 2. Obvious arrhythmia, cardiopulmonary function is not complete, 3. Mechanical ventilation, airway pressure higher than 40 MMHG, 4. Extensive peripheral arterial occlusive disease, 5. Severe liver and kidney disease, 6. Difficult intubation (> 2 intubations by experienced anesthesiologists), 7. Refused to patients and their families.

Design outcomes

Primary

MeasureTime frame
Pulse pressure variability (PPV);Oxygenation index;

Secondary

MeasureTime frame
Mean arterial pressure;Liquid measure during operation;

Countries

China

Contacts

Public ContactJun Yao

Shanghai Sixth People's Hospital

guoxinger@126.com+86 189 3017 3671

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026