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Observation on the Effect of Low-Dose Esketamine Combined with Propofol on Depressive Mood in Pediatric Tumor Patients Undergoing General Anesthesia for Bone Marrow Puncture

Observation on the Effect of Low-Dose Esketamine Combined with Propofol on Depressive Mood in Pediatric Tumor Patients Undergoing General Anesthesia for Bone Marrow Puncture

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113723
Enrollment
Unknown
Registered
2025-12-02
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Anesthesia

Interventions

Control Group:None
Observation Group:None

Sponsors

Children’s Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
4 Years to 16 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 4 and 16 years; 2. Pediatric patients initially diagnosed with a tumor and scheduled to undergo bone marrow puncture under general anesthesia; 3. American Society of Anesthesiologists (ASA) physical status classification of I to III; 4. Legal guardians fully understand the study, voluntarily participate, and provide signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Age >16 years or <4 years; 2. American Society of Anesthesiologists (ASA) physical status classification IV–V; 3. History of psychological disorders or psychiatric diseases; 4. Use of medications affecting the central nervous system; 5. Patients with impaired consciousness; 6. Patients with elevated intracranial pressure; 7. Patients with elevated intraocular pressure; 8. Patients with congenital heart disease exhibiting right-to-left shunt.

Design outcomes

Primary

MeasureTime frame
Depression Score ;

Secondary

MeasureTime frame
Incidence of Hypoxemia;Emergence Time;

Countries

China

Contacts

Public ContactJinmeng Gao

Children’s Hospital of Soochow University

gaojinmeng@163.com+86 512 8069 1319

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026