Painless prostate biopsy
Conditions
Interventions
R group:Propofol and Remifentanil
E group:Propofol and Esketamine
O group:Propofol and Ozelidine
Sponsors
Shanghai Changhai Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for transperineal prostate biopsy; 2. Age 18–85 years; 3. Body Mass Index (BMI) 18–30 kg/m^2 ; 4. American Society of Anesthesiologists (ASA) classification I–III; 5. Preoperative assessment indicates no difficult airway.
Exclusion criteria
Exclusion criteria: 1. History of severe heart, brain, lung, liver, kidney, or metabolic diseases; 2. Patients with gastrointestinal obstruction; 3. History of acute respiratory inflammation within the past 2 weeks that has not been cured; 4. Individuals with neuromuscular system disorders or mental illnesses; 5. Suspected abuse of narcotic analgesics or sedatives; 6. Predicted or previous occurrence of difficult airway; 7. Known allergy to remifentanil, esketamine, or oliceridine; 8. Concurrent use of other sedative or analgesic drugs within 15 minutes before, during, or after surgery (including injections, oral medications, and related traditional Chinese medicine preparations); 9. Individuals who are uncooperative or unable to communicate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient and operator satisfaction;Administer an additional dose of propofol;Degree of respiratory depression;Loop parameter;Adverse reaction;Does body movement affect the operation?;Wake-up time;Surgery time; | — |
Countries
China
Contacts
Public ContactYi Zhou
Shanghai Changhai Hospital
Outcome results
None listed