Femoral fracture
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years; 2. ASA (American Society of Anesthesiologists) physical status classification II-III; 3. Planned elective open reduction and intramedullary nail fixation for femoral fracture; 4. Voluntarily willing to participate in this study and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe liver dysfunction (Child-Pugh class C) or renal dysfunction (chronic kidney disease stage 4-5); 2. Severe cardiovascular or pulmonary disease, such as heart failure class III-IV (NYHA classification) or severe chronic obstructive pulmonary disease; 3. Clear history of psychiatric disorders, dementia, or delirium before surgery, unable to cooperate with study assessments; 4. Known coagulation disorders (INR > 1.4, platelet count < 80 × 10^9/L) or tendency to bleed; 5. Having an immune system disease, or long-term use of glucocorticoids or immunosuppressants; 6. History of acute myocardial infarction within the past 6 months; 7. Allergic to local anesthetics used in the study (lidocaine, ropivacaine) or postoperative analgesics; 8. Infection, tumor, or anatomical abnormalities at the puncture site, making safe implementation of SGB impossible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tumor necrosis factor;Interleukin-6;C-reactive protein;White Blood Cell Count; | — |
Secondary
| Measure | Time frame |
|---|---|
| CAM scale scoring;AIS Scale Score;VAS score; | — |
Countries
China
Contacts
Fengjie People's Hospital, Chongqing