Spine Fracture
Conditions
Interventions
High-Flow Nasal Cannula Group:High-Flow Nasal Cannula was used for oxygenation during the entire period of Total Intravenous Anesthesia.
Endotracheal Intubation Group:Oxygen was administered via endotracheal intubation with mechanical ventilation throughout Total Intravenous Anesthesia (TIVA).
Sponsors
Sir Run Run Hospital Nanjing Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.Age 65 years or older; 2.American Society of Anesthesiologists (ASA) Physical Status Classification of I, II, or III; 3.Body Mass Index (BMI) >=18 kg/m^2 and < 30 kg/m^2; 4.Scheduled to undergo Percutaneous Kyphoplasty (PKP) or Percutaneous Vertebroplasty (PVP) under Total Intravenous Anesthesia (TIVA).
Exclusion criteria
Exclusion criteria: 1.Severe systemic diseases (e.g., heart failure, ARDS); 2.Hemoglobin (Hb) level < 90 g/L; 3.Recent acute upper respiratory infection or pulmonary infection; 4.Nasal stenosis or deviated nasal septum; 5.Long-term use of benzodiazepines; 6.Anticipated difficult airway; 7.Chronic alcoholism; 8.Psychiatric disorders or communication difficulties; 9.History of allergy to the related anesthetic agents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The lowest SpO2 value during anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Hypoxemia;Intraoperative MAP, HR, SpO2;(PHPaO2PaCO2PaO2/FiO2Lac);QoR-15 score;Emergence time; PACU length of stay; Operative time; Hospital length of stay; Time to first ambulation; Time to first flatus.;Intraoperative medication usage (dosages of remimazolam, remifentanil, vasoactive agents, etc.);Surgeon satisfaction score; Patient satisfaction score; | — |
Countries
China
Contacts
Public ContactWang Liang
Sir Run Run Hospital Nanjing Medical University
Outcome results
None listed