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The Association Between Plasma Ergothioneine and Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery: A Prospective Cohort Study

The Association Between Plasma Ergothioneine and Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery: A Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113684
Enrollment
Unknown
Registered
2025-12-02
Start date
2025-12-10
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

POD group:None
Non-POD group:None

Sponsors

Hebei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1.Patients aged >= 65 and = 24.

Exclusion criteria

Exclusion criteria: 1.Patients with a known allergy to any anesthetic drugs used in this study; 2.Patients with a history of NYHA Class III-IV heart failure, second or third-degree atrioventricular block, atrial fibrillation, or bronchial asthma; 3.Patients with severe hepatic or renal insufficiency; 4.Patients with a history of severe psychiatric disorders, including dementia, organic mental disorders, or other psychiatric conditions accompanied by mental impairment, as well as those with communication difficulties; 5.Patients with a history of gastrointestinal surgery or chronic malabsorption diseases (e.g., inflammatory bowel disease, celiac disease); 6.Voluntary withdrawal requested by the patient or their authorized representative.

Design outcomes

Primary

MeasureTime frame
Ergothioneine;

Countries

China

Contacts

Public ContactLi Jianli

Hebei General Hospital

hblijianli@163.com+86 311 85988447

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026