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Associations of Paternal and Maternal Preconception Exposures with Offspring Allergic Rhinitis Risk: A Retrospective Case-Control Study Based on the DOHaD Theory

Associations of Paternal and Maternal Preconception Exposures with Offspring Allergic Rhinitis Risk: A Retrospective Case-Control Study Based on the DOHaD Theory

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113681
Enrollment
Unknown
Registered
2025-12-02
Start date
2025-12-15
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis

Interventions

Case Group:None
Control Group:None

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Case Group: 1.Diagnosed with allergic rhinitis according to the diagnostic criteria for childhood allergic rhinitis in the "Chinese Guidelines for Diagnosis and Treatment of Allergic Rhinitis in Children (2022 Revision)," confirmed by clinical symptoms and allergen testing. 2.Parents could provide complete prenatal exposure information. Control Group: 1. Matched with the case group in age and sex. 2. Not diagnosed with allergic rhinitis or other allergic diseases by a physician. 3.Parents could provide complete prenatal exposure information.

Exclusion criteria

Exclusion criteria: Excluded from the Case Group: 1.Diagnosed with non-allergic rhinitis (e.g., vasomotor rhinitis, infectious rhinitis, atrophic rhinitis, drug-induced rhinitis). 2.Incomplete, contradictory, or unidentifiable questionnaire information. Excluded from the Control Group: 1.Diagnosed with allergic rhinitis or other allergic diseases. 2. Incomplete, contradictory, or unidentifiable questionnaire information.

Design outcomes

Primary

MeasureTime frame
Has the participant been diagnosed with allergic rhinitis;

Countries

China

Contacts

Public ContactPeng Lu

Children's Hospital of Chongqing Medical University

penglu19890217@outlook.com+86 133 5031 2525

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026