Postoperative delirium
Conditions
Interventions
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
Male
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Male aged 60 and above; 2. Non-cardiac surgery is planned to be performed under general anesthesia; 3. Sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.History of dementia, schizophrenia, or Parkinson’s disease. 2.ASA physical status = IV. 3.Severe hepatic dysfunction (Child–Pugh class C). 4.Severe renal dysfunction requiring pre-operative dialysis. 5.Men with pituitary or testicular disorders, or those currently using androgens, anti-androgens, 5a-reductase inhibitors, estrogens, anti-estrogens, or progestogens. 6. Participants with pre-existing delirium or cognitive impairment: defined by MMSE score 6 years of education).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality within 30 days after the operation;The incidence of non-delirium complications within 30 days after the operation;The incidence of surgical infection complications within 30 days after the operation;Postoperative hospital stay;The incidence of postoperative cognitive dysfunction (T-MoCA score decreased by >=1SD compared with that before the operation) 30 days after the operation;PACU dwell time;The incidence of delirium during the recovery period; | — |
Countries
China
Contacts
Public ContactLuo Tao
Peking University Shenzhen Hospital
Outcome results
None listed