Ovarian Endometriosis
Conditions
Interventions
Experimental Group:The treatment group receives oral Chang'e Jiali Wan. Subjects are assigned to different study groups according to a random number table.Medication administration starts on the 1st d
Sponsors
Obstetrics and Gynecology Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: The subjects must meet all of the following criteria: 1.The clinical diagnosis is considered as ovarian chocolate cyst (unilateral, maximum diameter <=5cm) through ultrasound /MRI imaging examination. 2. Women of childbearing age aged 20 to 40 who have recent fertility needs; 3. Regular menstrual cycle (28+/-7 days); 4. The subject agrees to sign the informed consent form. When the subject is unable to read the content of the informed consent form, it must be signed jointly with a notarized witness.
Exclusion criteria
Exclusion criteria: Subjects cannot be enrolled if they meet any of the following criteria: 1.AMH 2.28nmol/L (50µg/L)), hypogonadotropic hypogonadism, poorly controlled thyroid diseases (TSH not within the normal reference range), Addison's disease, systemic lupus erythematosus, Crohn's disease, and poorly controlled diabetes (glycated hemoglobin [H bA1c > the upper limit of the normal reference value, etc. 4. Patients with unexplained vaginal bleeding that has not been cured and those with endometrial hyperplasia; 5. Patients with severe primary diseases such as cardiovascular and cerebrovascular insufficiency, liver and kidney dysfunction, and hematopoietic and coagulation system disorders; 6. Those who have received Chinese or Western medicines or health supplements for improving decreased ovarian reserve function within 14 days prior to screening, or who do not agree to stop using the above-mentioned medicines during the trial period; 7. Those with malignant or benign tumors of the reproductive organs requiring surgical treatment, or those with breast tumors; 8. Those who meet one of the following indicators during the screening period: aspartate aminotransferase (AST) or alanine aminotransferase (ALT) > 1.5 times the upper limit of the normal reference value, or serum creatinine (Scr) > the upper limit of the normal reference value; 9. There are factors causing tubal infertility or the male partner has factors that lead to infertility; 10. Those who the researchers consider unsuitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine or blood HCG positive;Ultrasound detection of embryo and fetal heart (+); | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Sex Hormone Levels;Anti-Müllerian Hormone (AMH) Level;Serum Tumor Marker CA125 Level;Antral follicle counting,AFC;Ovarian volume,OVVOL;Number of Dominant Follicles; Endometrial Thickness During Ovulation;Size of Ovarian Chocolate Cyst;Visual analogue scale, VAS; | — |
Countries
China
Contacts
Public ContactWang Li
Obstetrics and Gynecology Hospital Affiliated to Fudan University
Outcome results
None listed