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Clinical application of dexketoprofen trometamol injection in patients undergoing hysteroscopic surgery without opioid anesthesia: A prospective, randomized, controlled trial

Clinical application of dexketoprofen trometamol injection in patients undergoing hysteroscopic surgery without opioid anesthesia: A prospective, randomized, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113664
Enrollment
Unknown
Registered
2025-12-01
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia and analgesia protocol for hysteroscopic surgery

Interventions

Experimental Group:Dexketoprofen trometamol injection 50mg for intravenous pump infusion over 20 minutes
Control Group:Flurbiprofen axetil injection 50mg for intravenous pump infusion over 20 minutes

Sponsors

Baiyun District People's Hospital of Guangzhou
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily participate in this research; 2.ASA (American Society of Anesthesiologists) Grade I - II; 3. Age between 18 and 65; 4. Body mass index is between 18.5 and 23.9kg/m ²; 5. Patients who are scheduled to undergo hysteroscopic surgery under general anesthesia (without intubation) in the operating room (with an estimated duration of less than 2 hours).

Exclusion criteria

Exclusion criteria: 1.Patients with relevant anesthesia contraindications and those with contraindications to the drugs and devices used in this study; 2. Those with mental disorders or other conditions that prevent them from communicating with medical staff; 3. Those with severe organ lesions or sleep apnea syndrome; 4. Those with systemic infectious diseases.

Design outcomes

Primary

MeasureTime frame
Number of patient movements;Surgeon satisfaction levels;Total dosage of propofol;Waking time;QoR-15 Score (Quality Recovery Rating Scale-15);

Secondary

MeasureTime frame
Types of treatments and their frequencies in cases of respiratory depressio;Procedures to be followed in case of low blood pressure, as well as the frequency of such occurrences.;Length of hospital stay and related costs;Vital signs (peripheral blood oxygen saturation, systolic/diastolic blood pressure, pulse rate, respiration, body temperature);General information: ASA classification, age, gender, height, weight/weight index, preoperative comorbidities, history of smoking and alcohol consumption, hemoglobin concentration.;Number of episodes of respiratory depression (peripheral blood oxygen saturation = 90%);

Countries

China

Contacts

Public ContactBinming Qiu

Baiyun District People's Hospital of Guangzhou

435130702@qq.com+86 189 2896 8081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026