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Construction and Empirical research of exercise-cognitive intervention Program for hospitalized elderly patients with depression complicated with cognitive frailty based on evidence

Construction and Empirical research of exercise-cognitive intervention Program for hospitalized elderly patients with depression complicated with cognitive frailty based on evidence

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113655
Enrollment
Unknown
Registered
2025-12-01
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Frailty (CF)

Interventions

CST Group:Using a group exercise format, it activates multiple cognitive domains such as episodic memory, executive function, and semantic processing through life-like scenarios. The thematic activiti
ME+CST group:The intervention uses a group exercise format, with participants in the CST group receiving ME training. The entire exercise intervention takes place indoors, and medical graduate student
Control group:Patients in the control group received routine nursing interventions

Sponsors

The Second Affiliated Hospital of Xinxiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Simultaneously meeting the diagnostic criteria for LLD and CF: (1) Meeting the diagnostic criteria for depression in the 10th edition of the International Classification of Diseases (ICD-10); (2) In the pre-frailty stage or frailty period, with an FP scale score of >=1; (3)MCI or subjective cognitive decline (SCD), with a score of 18 to 26 on the Montreal Cognitive Assessment Scale (MoCA) Or MoCA>27 points and SCD positive. 2.Age over 60. 3.Those who voluntarily participate and actively cooperate.

Exclusion criteria

Exclusion criteria: 1.There are advanced, severe, acute, subacute or unstable organic brain diseases or physical diseases that affect the observation of indicators and safety. 2.Diagnosed with Alzheimer's disease or other types of dementia: Meets the diagnostic criteria for severe neurocognitive impairment in the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) of the United States. 3.Those with a history of other mental illnesses. 4.In the past two weeks, I have taken drugs that can cause cognitive changes, balance disorders or damage to important organs. 5.Activities of daily living (Barthel index) <50 points, independent standing and walking ability <10 meters.

Design outcomes

Primary

MeasureTime frame
Perceived Social Self Effcacy, PSSE;Frailty Phenotype, FP;General Information;Timed Up and Go, TUGT;Montreal Cognitive, MoCA;Modified Fall Efficacy;Hamilton Depression,HAMD;

Countries

China

Contacts

Public ContactLi Jie

The Second Affiliated Hospital of Xinxiang Medical University

ljie0914@163.com+86 373 337 3985

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026