bisphosphonate related osteonecrosis of the jaw
Conditions
Interventions
Observation group:none
Sponsors
Beijing Stomatological Hospital , Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Age:>30 years old and<60 years old; 2.Gender: Male or female, no restrictions; 3.Adequate bone mass at the implantation site; 4.No history of radiotherapy and chemotherapy of jaw bone, no history of hepatitis, AIDS and other infectious diseases, no family genetic history;
Exclusion criteria
Exclusion criteria: 1.Patients with uncontrolled periodontitis; 2.Patients who have undergone heart valve replacement surgery and those who have experienced myocardial infarction within 6 months; 3.Patients taking anticoagulant drugs or other medications that can cause coagulation dysfunction; 4.Patients with acute inflammation of any infection, such as acute inflammation of the respiratory tract; 5.Patients with psychological/psychiatric disorders present; 6.Patients with blood disorders, such as hemophilia, thrombocytopenia, acute leukemia, etc., who exhibit coagulation dysfunction; 7.Patients taking bisphosphonates; 8.Patients with diabetes; 9.Pregnant and lactating women; 10.Patients with intellectual disabilities; 11.Smoking patients;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of IGFBP2 expression on the biological functions of patients' bone marrow mesenchymal stem cells; | — |
Countries
China
Contacts
Public ContactLingxiao Wang
Beijing Stomatological Hospital , Capital Medical University
Outcome results
None listed