Post-Laparoscopic Colorectal Cancer Surgery
Conditions
Interventions
Sham taVNS group:Perioperative management of colorectal cancer+sham taVNS
taVNS group:Perioperative management of colorectal cancer+taVNS
Sponsors
Nanjing Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18-85 years, no restriction on gender; 2. Patients scheduled for elective laparoscopic radical resection of colorectal cancer with primary anastomosis; 3. Newly diagnosed patients (defined as: first confirmed diagnosis of colorectal cancer, no prior tumor-related treatment before surgery, including neoadjuvant chemotherapy, neoadjuvant radiotherapy, targeted therapy, or immunotherapy); 4. Undergoing abdominal surgery for the first time; 5. General anesthesia, meeting American Society of Anesthesiologists (ASA) classification I-III; 6. Auricular skin intact, without damage, inflammation, eczema, or scars; 7. Elderly subjects aged 65-85 must complete the Mini-Mental State Examination (MMSE) screening, with a score >=20.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart, liver, kidney dysfunction, or mental illness; 2. Patients undergoing palliative surgery or emergency surgery; 3. Patients requiring combined resection of other organs; 4. Patients who experience serious complications during surgery (anastomotic leakage, gastrointestinal bleeding); 5. Patients whose laparoscopic surgery fails and require conversion to open surgery; 6. Patients with external stomas; 7. Patients with implanted electronic devices such as pacemakers or insulin pumps; 8. Pregnant or breastfeeding women; 9. Patients simultaneously participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Achievement rate of GI-3 within 72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first postoperative anal flatus;Time to first postoperative defecation;Time to postoperative bowel sound appearance;Time to normalization of postoperative bowel sounds;Time to first postoperative water intake;Time to tolerance of postoperative liquid diet;Time to tolerance of postoperative solid diet;Time to first postoperative ambulation;Postoperative length of hospital stay;Time to initiation of independent postoperative ambulation;Number of episodes of nausea, vomiting, and bloating;Severity of postoperative pain; | — |
Countries
China
Contacts
Public ContactZhang Yang
Nanjing Hospital of Traditional Chinese Medicine
Outcome results
None listed