sepsis
Conditions
Interventions
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Criteria for patients with sepsis: The subtypes of sepsis are defined according to the 2021 International Guidelines for the Management of sepsis and septic shock; All participants are of Han ethnicity in China and are over 18 years old. 2. Health control criteria: No recent acute diseases, autoimmune diseases, hypertension, diabetes, cancer or major chronic diseases such as heart, kidney, liver and endocrine diseases, and no history of sepsis;
Exclusion criteria
Exclusion criteria: 1.Sepsis group: Patients with a history of malignant tumors, human immunodeficiency virus, autoimmune diseases, blood disorders, or other organic diseases are excluded. Age < 2.Under 18 years old, decreased granulocyte count (< 500/µl), death within 24 hours after admission to the ICU; 3.Healthy control group: Recent acute diseases, autoimmune diseases, immune deficiency syndrome, cancer or major chronic diseases such as heart, kidney, liver and endocrine diseases, and a history of sepsis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil surface EGFR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Procalcitonin (PCT);tumor necrosis factor -a (TNF-a), interleukin-1 ß (IL-1ß), and interleukin-6 (IL-6) in peripheral blood; | — |
Countries
China
Contacts
Public ContactJing Tang
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed