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Individualized Blood Pressure Management Based on Multimodal Brain Function Monitoring:The Impact of Willis Circle Compensation Capacity on Postoperative Delirium and Stroke in CEA Patients

Individualized Blood Pressure Management Based on Multimodal Brain Function Monitoring:The Impact of Willis Circle Compensation Capacity on Postoperative Delirium and Stroke in CEA Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113612
Enrollment
Unknown
Registered
2025-12-01
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid artery stenosis

Interventions

Willis Circle Compensatory Cohort:None
Circle of Willis Inadequate Cohort:None

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Undergoing carotid endarterectomy under general anesthesia on an elective basis. 2. Age > 18 years old, gender not restricted. 3. ASA II or III grade.

Exclusion criteria

Exclusion criteria: 1. The patient or the patient's family refuses to participate in this trial. 2. Those with preoperative consciousness disorders or cognitive impairments. 3. Patients who experienced preoperative delirium. 4. Patients with visual or auditory impairments who cannot accurately complete the assessment. 5. Those who are heavy drinkers, have been addicted to sedatives or analgesics for a long time. 6. CTA examination failed to show the distal part of intracranial arteries.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium;Stroke;

Secondary

MeasureTime frame
Cerebral oximetry index;rSO2;MCA Vm;IL-6;NfL;Montreal Cognitive ;

Countries

China

Contacts

Public ContactHuang Lining

The Second Hospital of Hebei Medical University

15803213730@163.com+86 158 0321 3730

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026