Myopia
Conditions
Interventions
0.01% Atropine Group:Use 0.01% atropine eye drops once daily at night.
0.025% Atropine Group:Use 0.025% atropine eye drops once daily at night.
0.05% Atropine Group:Use 0.05% atropine eye drops once daily at night.
Sponsors
Henan Provincial Eye Hospital
Eligibility
Sex/Gender
All
Age
8 Years to 12 Years
Inclusion criteria
Inclusion criteria: (1) Age between 8 and 12 years old (inclusive of the boundary values). (2) After cycloplegia (compound tropicamide eye drops), binocular spherical refraction measured by computerized refractometry: -4.00D =4.9, with a difference in best-corrected visual acuity between eyes <= 0.1. (4) Voluntary participation in this trial, ability to communicate effectively with the investigator and comply with all trial requirements, and submission of a written informed consent form signed by the child or legal guardian.
Exclusion criteria
Exclusion criteria: (1) patients with central nervous system diseases, Down's syndrome, epilepsy, craniocerebral injury, asthma, congenital heart disease and other serious systemic diseases. (2) may have eye diseases affecting vision or diopter (such as cataract or other lens diseases, glaucoma, corneal diseases, uveitis, retinal and vitreous diseases). (3) strabismus and amblyopia. (4) acute infectious eye diseases. (5) myopic medication (including atropine, pelenzepine, anisodamine, etc.) or device therapy for myopia within 3 months; Wear functional glasses or orthokeratology lenses. (6) Allergic to cycloplegic atropine, Saberjet or compound tropicamide eye drops. (7) previous strabismus surgery, refractive surgery or intraocular surgery. (8) Intraocular pressure (IOP) > 21mmHg. (9) participated in another clinical trial within 30 days before screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Axial length;Refractive power; | — |
Secondary
| Measure | Time frame |
|---|---|
| Retinal defocus state;The Accommodation Function ;Choroidal thickness; | — |
Countries
China
Contacts
Public ContactLei Zhu
Henan Provincial Eye Hospital
Outcome results
None listed