Gallstone
Conditions
Interventions
Group ESPB:Received ultrasound-guided bilateral T7 erector spinae nerve block, with 0.33% ropivacaine, 15 ml for each side.
Control group:General anesthesia with a simple laryngeal mask
Sponsors
Rikaze City People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age: 18 - 65 years old; 2. BMI: 18.5 - 28 kg/m^2; 3. Permanent residents of Xizang (residing at an altitude of > 3000m for >= 6 months); 4. Patients diagnosed with gallbladder stones; 5. Scheduled for laparoscopic cholecystectomy; 6. Resting SpO2 >= 85% (in high-altitude environment); 7. ASA classification: I - III grade
Exclusion criteria
Exclusion criteria: 1. Anesthesia-related contraindications (1). History of local anesthetic allergy or contraindications to the use of amide-type local anesthetics; (2). Presence of infection, deformity or space-occupying lesion in the puncture area; (3). Abnormal coagulation function (INR > 1.5 or PLT 5 points (refer to the Lake Louise standard); (3).Hematocrit (Hct) > 65% (uncontrolled high-altitude polycythemia). 4. Other exclusion factors (1). Long-term use of opioid drugs (>30mg/day morphine equivalent dose); (2). Mental illness or cognitive impairment (unable to cooperate with pain assessment); (3).Pregnant or lactating women; (4).Other situations judged by the researchers as not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The resting VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The resting VAS score 1 hours after the operation;Cortisol ;Tumor necrosis factor alpha 4 hours after surgery;IL-6 level ;The amount of remifentanil used during the operation;cTnI;Oxygenation function;The time from the end of the surgery to the removal of the tube;The first post-remedy analgesic relief time; | — |
Countries
China
Contacts
Public ContactZhang Qingfu
Rikaze People's Hospital
Outcome results
None listed