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The Effects of Scleral Contraction on Retinal Structure, Function, and Three-Dimensional Ocular Morphology in Patients with Pathological Myopia

The Effects of Scleral Contraction on Retinal Structure, Function, and Three-Dimensional Ocular Morphology in Patients with Pathological Myopia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113588
Enrollment
Unknown
Registered
2025-12-01
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High myopia

Interventions

Scleral Contraction Group:Scleral Contraction

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Participants who are fully informed and voluntarily agree to participate in this study, aged 8-70 years. 2. Pathological myopia patients with a refractive error of = 26.0mm, and associated with MTM. 3. Magnetic resonance imaging (MRI) shows the presence of posterior scleral staphyloma.

Exclusion criteria

Exclusion criteria: 1. Patients with severe systemic diseases, such as autoimmune diseases or severe cardiovascular and pulmonary diseases. 2. Patients with active ocular inflammatory diseases. 3. Patients with refractive media opacity affecting fundus imaging or poor imaging quality in OCT and OCTA examinations. 4. Patients with ocular tumors or other diseases or surgeries that may affect the shape of the eyeball. 5. Patients with metal implants in the body or claustrophobia who are unable to undergo magnetic resonance imaging (MRI).

Design outcomes

Primary

MeasureTime frame
Axial length;

Secondary

MeasureTime frame
Intraocular pressure, OCTA, 3D MRI;Best corrected visual acuity;OCT;

Countries

China

Contacts

Public ContactRuihua Wei

Tianjin Medical University Eye Hospital

weirhua2009@126.com+86 139 2068 5016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026