Sarcopenia
Conditions
Interventions
Sarcopenia group:None
Sponsors
Jilin Provincial First Automobile General Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: A total of 200 elderly patients (aged over 60) who were hospitalized in our hospital from January 2026 to December 2026 were included, and they all signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Neurological disorders: Alzheimer’s disease, Parkinson’s disease, history of stroke, or use of neuroactive drugs within the past 6 months; 2.Psychiatric disorders: Depression, schizophrenia; 3.Conditions or treatments affecting muscle metabolism: Malignant tumors, severe heart failure, endstage renal disease; current use of glucocorticoids, androgens, or growth hormone; receipt of immunosuppressants or chemotherapy within the past 3 months; 4.Major organ dysfunction:Severe liver disease (ChildPugh class B/C or ALT/AST > 3 × upper limit of normal);Renal insufficiency (eGFR < 30 mL/min/1.73 m²);Heart failure (NYHA class III–IV) or myocardial infarction within the past 6 months; 5.Inability to undergo bioelectrical impedance analysis (BIA), e.g., patients with implanted cardiac pacemakers or similar devices; 6.Conditions affecting grip strength, such as rotatorcuff injuries; 7.Inability to complete independent gait-speed testing, e.g., severe arthritis, visual impairment, balance disorders, etc;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hand-grip strength;Step speed;Geriatric Nutritional Risk Index (GNRI);Serum brain-derived neurotrophic factor (BDNF);Serum high-sensitivity C-reactive protein (hs-CRP);Appendicular skeletal muscle mass index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum albumin and other routine biochemical parameters; | — |
Countries
China
Contacts
Public ContactQi Dongxu
Jilin Provincial First Automobile General Hospital
Outcome results
None listed