Cognitive dysfunction
Conditions
Interventions
Control group:During surgical anesthesia, the control group (Group C) only underwent rSO2 monitoring during and after surgery, without any intervention or adjustment.
Experimental group:Before surgery, ultrasound-guided stellate ganglion block was performed on the same side as the surgery, and intraoperative and postoperative cerebral oxygen saturation monitoring w
Sponsors
Drum Tower Hospital, Affiliated to Nanjing University Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Imaging studies confirming Moyamoya disease; 2.normal mental and intellectual status, able to communicate and cooperate; 3.American Society of Anesthesiologists (ASA) physical status classification I-III; 4.Baseline blood pressure with systolic <180 mmHg and diastolic <110 mmHg; 5.Informed consent to participate in this study, with a signed informed consent form.
Exclusion criteria
Exclusion criteria: 1.Pre-existing severe conditions such as significant organ dysfunction; 2.Coagulation disorders, anemia; 3.Allergy to local anesthetics or other anesthetic agents; 4.inability to undergo SGB or presence of contraindications; 5.History of drug abuse; 6.Inability to cooperate and complete the study due to any other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of a decrease of =4 points in the Montreal Cognitive Assessment (MoCA) score compared to preoperative levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of a Mini-Mental State Examination (MMSE) score decrease of =3 points compared to preoperative levels;Incidence of neurological complications;The incidence of rSO2 fluctuations exceeding the target range;Postoperative pain and adverse reactions; | — |
Countries
China
Contacts
Public ContactGu Wei
Drum Tower Hospital, Affiliated to Nanjing University Medical School
Outcome results
None listed