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Electroencephalographic Features during Target-Controlled Infusion of Remimazolam for General Anesthesia Across Different Age Groups: A Prospective Cohort Study

Electroencephalographic Features during Target-Controlled Infusion of Remimazolam for General Anesthesia Across Different Age Groups: A Prospective Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113571
Enrollment
Unknown
Registered
2025-12-01
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

EEG

Interventions

Adult group(18-64years):None

Sponsors

Xiangya Hospital Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Patients aged between 18 and 85 who plan to undergo general anesthesia for non-cardiac major vascular or neurosurgical operations; 2. The subjects signed the informed consent form and possess certain communication skills; 3. Have a mild to moderate physical health condition (such as ASA grade I-III); 4. Routine laboratory tests in the body (such as liver and kidney functions, blood routine, etc.) are within the normal range or within the safe range after treatment and adjustment, and do not affect the anesthesia process; 5. No history of allergy to remimazolam or benzodiazepines; 6. There is no obvious history of heart and lung diseases, such as severe heart failure, acute coronary syndrome, severe hypertension, etc., and no serious respiratory system diseases.

Exclusion criteria

Exclusion criteria: 1.Patients who are allergic to benzodiazepines or any component of this product, patients with myasthenia gravis, patients with schizophrenia, and patients in a severe depressive state. 2. Patients with respiratory tract management difficulties (Modified Markov Scale grade IV). 3. Patients with a known history of severe angina pectoris attacks or arrhythmia in their previous medical history. 4. Patients with chronic renal failure and chronic liver damage. 5. Long-term alcoholics and drug users.

Design outcomes

Primary

MeasureTime frame
Time Domain Analysis;Time Frequency Analysis;Frequency Domain Analysis;

Secondary

MeasureTime frame
Patient State Index;

Countries

China

Contacts

Public ContactZhong Tao

Xiangya Hospital, Central South University

zhongtao@csu.edu.cn+86 731 8432 7411

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026