Crohn's disease
Conditions
Interventions
Index test:Super-Resolution Contrast-Enhanced Ultrasound?Contrast-enhanced Ultrasound?2D Ultrasound?Color Doppler Flow Imaging?Shear Wave Elastography
Sponsors
Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=18 years old, gender not limited; 2.Comply with the "Diagnostic Criteria for Crohn's Disease (2024 Edition)" of China, and be diagnosed with Crohn's disease through endoscopy, imaging (CT/MRI), and pathology; 3.The patient initiates a new treatment plan, including biologics or immunosuppressant therapy; 4.Endoscopic examination was performed within the last month; 5.Be capable of cooperating to complete multimodal ultrasound examinations including contrast-enhanced ultrasound; 6.Voluntarily sign the informed consent form and agree to participate in the research and data collection;
Exclusion criteria
Exclusion criteria: 1.Contrast agent allergy; 2.Complicated with severe complications or contraindications; 3.Pregnant or lactating women, and those with severe renal insufficiency; 4.Combined with other intestinal diseases, such as intestinal tuberculosis, intestinal tumors, or systemic immune diseases; 5.Abdominal obesity, BMI>=30kg/m², leads to poor ultrasound penetration and poor display of intestinal wall structure; 6.Poor image quality of contrast-enhanced ultrasound: During the examination, unstable images are caused by breathing and intestinal peristalsis, which affects the accuracy of quantitative parameters; 7.Incomplete data: The colonoscopy failed to reach the target section or the clinical data was incomplete; 8.Those who have undergone intestinal surgery within the past three months;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease remission period; | — |
Countries
China
Contacts
Public ContactLi Gong
Nanjing Drum Tower Hospital
Outcome results
None listed