Seasonal Influenza
Conditions
Interventions
Control group [single infected individuals]:None
Research group [repeated infections]:None
Sponsors
The Fifth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Research Group [Repeatedly Infected Individuals] : 1. Age and gender are not limited. 2. Fever (body temperature >=38?), accompanied by either cough or sore throat; 3. Confirmed as having influenza through influenza virus antigen testing or/and influenza virus nucleic acid testing; 4. Two laboratory confirmations, with an interval of four weeks between confirmations 5. Complete clinical information. Control group [Single infection] : 1. Age and gender are not limited. 2. Fever (body temperature >=38?), accompanied by either cough or sore throat; 3. Confirmed as having influenza through influenza virus antigen testing or/and influenza virus nucleic acid testing; 4. There has been no recurrence record within 12 months after the first diagnosis. 5. Complete clinical information.
Exclusion criteria
Exclusion criteria: 1.Failure to undergo influenza virus antigen testing or influenza virus nucleic acid testing; 2.People with immunodeficiency diseases or long-term use of immunosuppressants; 3.Tumor patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference of hs CRP level and dynamic changes of immune cells between experimental group and control group;Clinical application performance of multimodal risk prediction model; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative incidence of chronic diseases and comorbidity of multiple chronic diseases in experimental group and control group;Risk ratio (HR) and average treatment effect (ATE) after adjusting for confounding factors; | — |
Countries
China
Contacts
Public ContactGuanmin Jiang
The Fifth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed