Non small cell lung cancer
Conditions
Interventions
Early onset lung cancer group VS Late onset lung cancer group:none
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Retrospective study Inclusion criteria: 1. Pathologically confirmed primary non-small cell lung cancer; 2. Underwent radical lung cancer resection; 3. Early onset lung cancer group: the age at diagnosis was greater than or equal to 14 years old and less than or equal to 30 years old; 4. Late onset lung cancer control group: older than or equal to 65 years at the time of diagnosis; Prospective study Inclusion criteria: 1. Pathologically confirmed primary non-small cell lung cancer; 2. Did not receive any anti-tumor treatment such as radiotherapy, chemotherapy, targeted therapy, immunotherapy before surgery; 3. No smoking history; 4. Early onset lung cancer group: the age at diagnosis was greater than or equal to 14 years old and less than or equal to 30 years old; 5) Late onset lung cancer control group: older than or equal to 65 years at the time of diagnosis.
Exclusion criteria
Exclusion criteria: Retrospective study Exclusion criteria: 1. Previous history of pulmonary fibrosis, tuberculosis, COPD; 2. Exposure history of asbestos, beryllium, uranium, radon, etc; 3. Concurrent other primary malignancies at diagnosis; 4. Key clinical information missing or patients lost to follow-up. Prospective study Exclusion criteria: 1. Previous history of pulmonary fibrosis, tuberculosis, COPD; 2. Exposure history of asbestos, beryllium, uranium, radon, etc; 3. Concurrent other primary malignancies at diagnosis; 4. The collected samples did not meet the sequencing conditions; 5. Key clinical information missing or patients lost to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease free survival;Frequency of genetic mutations in germ lines and somatic cells associated with hereditary cancer syndrome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival, OS;Lung Cancer–Specific Survival; | — |
Countries
China
Contacts
Public ContactJian Zhou
West China Hospital of Sichuan University
Outcome results
None listed