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Risk factor analysis and precise prediction model construction for osteoporotic fractures

Risk factor analysis and precise prediction model construction for osteoporotic fractures

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500113541
Enrollment
Unknown
Registered
2025-12-01
Start date
2025-12-04
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis

Interventions

Gold Standard:Diagnostic Criteria for Osteoporosis in the Guidelines for the Diagnosis and Treatment of Primary Osteoporosis (2022 Edition)
Index test:fracture risk assessment tool, FRAX®

Sponsors

Xiangya Second Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age between 40 and 90 years old; 2. Meets the diagnostic criteria for osteoporosis in the "Guidelines for Diagnosis and Treatment of Primary Osteoporosis" (version 2022); 3. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Violent fractures caused by car accidents, falls from heights, and pathological fractures caused by tumor bone metastasis; 2. Combined with other diseases that may seriously affect bone or soft tissue metabolism, such as type 1 diabetes, hyperthyroidism, bone tuberculosis, multiple myeloma, etc; 3. Long term use of hormones, chemotherapy drugs, aromatase inhibitors, etc; 4. Severe heart and lung disease or liver and kidney dysfunction, after organ transplantation; 5. Personal information and data are incomplete.

Design outcomes

Primary

MeasureTime frame
complete blood count;Glucose metabolism indicators;Bone turnover markers;Bone density;

Secondary

MeasureTime frame
Liver metabolic indicators;Renal function indicators;Lipid metabolism indicators;Blood calcium and phosphorus;Sex hormone;Cortisol;

Countries

China

Contacts

Public ContactHoude Zhou

Xiangya Second Hospital of Central South University

houdezhou@csu.edu.cn+86 137 8722 4738

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026