Lung diseases
Conditions
Interventions
Experimental group (Olicerlidine):The PCA regimen consisted of oliceridine (25 mg) and tropisetron (5 mg) in normal saline (total volume 100 mL), with 2 mL loading dose, 2 mL·h?1 continuous infusion,
control group (Sufentanil):The PCA regimen consisted of sufentanil (100µg) and tropisetron (5 mg) in normal saline (total volume 100 mL), with 2 mL loading dose, 2 mL·h?1 continuous infusion, 0.5 mL d
Sponsors
Jianyang City People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age = 18 years, regardless of gender; 2. Patients scheduled for elective thoracic surgery; 3. ASA physical status classification I-III; 4. Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1. Anticipated hospital stay duration of less than 48 hours; 2. Patients expected to require ICU admission postoperatively; 3. Presence of contraindications to nerve block procedures; 4. Pregnant or lactating patients; 5. Individuals with known hypersensitivity to oxaliplatin;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Static and dynamic NRS scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| 15-item Quality of Recovery Scale (QoR-15) score;PCA demand attempts,Rescue analgesia requirements;Postoperative Nausea and Vomiting;satisfactory analgesia with minimal emesis, SAME; | — |
Countries
China
Contacts
Public ContactShang Ziqi
Jianyang City People's Hospital
Outcome results
None listed