Pharyngoesophageal Fistula
Conditions
Interventions
Experimental Group:During total laryngectomy, TNPT was placed in the lower pharynx. After the operation, negative pressure aspiration was continuously performed for one week, with a negative pressure
Control group:The patient was treated surgically in accordance with the conventional procedure of total laryngectomy.
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) The age of participants must be between 18 and 80 years; 2) Due to the needs of the condition, total laryngectomy must be performed; 3) Participants should be in good overall health, able to tolerate general anesthesia and surgery, and the Eastern Cooperative Oncology Group (ECOG) performance status score should not exceed 2; 4) Participants must be willing and able to comply with the visit, treatment plan, and other related research procedures in the study protocol.
Exclusion criteria
Exclusion criteria: 1) At the same time, there are other serious diseases that need to be effectively controlled, such as tuberculosis, leprosy, etc.; 2) Accompanied by severe abnormalities in the functions of important organs such as the heart, brain, and lungs; 3) Do not agree to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pharyngocutaneous fistula incidence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complication rate;Quality of Life Score; | — |
Countries
China
Contacts
Public ContactZhangwei Hu
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed