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A Randomized, Double-Blind, Placebo-Controlled Study on the Effects of Preoperative Use of Medical Oral Rinse on Postoperative Dry Mouth and Early Recovery Quality in Elderly Patients Undergoing Lung Surgery under General Anesthesia

A Randomized, Double-Blind, Placebo-Controlled Study on the Effects of Preoperative Use of Medical Oral Rinse on Postoperative Dry Mouth and Early Recovery Quality in Elderly Patients Undergoing Lung Surgery under General Anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113507
Enrollment
Unknown
Registered
2025-12-01
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry mouth postoperative

Interventions

MOR group:2 h before the surgery, patients are to rinse their mouth twice with 15 mL of the solution for 30 seconds and then expectorate.
NS group:2 h before the surgery, patients are to rinse their mouth twice with 15 mL normal saline for 30 seconds and then expectorate.

Sponsors

Taizhou People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 65-80 years; 2. Scheduled for elective lung surgery (lobectomy/segmentectomy/wedge resection), including minimally invasive and open thoracic surgery; 3. American Society of Anesthesiologists (ASA) classification I-III; 4. Voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Severe dry mouth, active oral infection, or oral mucosal damage before surgery; 2. Severe liver or kidney dysfunction (Child-Pugh class C or eGFR < 30 ml/min/1.73m²); 3. Active pulmonary infection before surgery; 4. Cognitive impairment or inability to cooperate with study assessments; 5. Allergy to any components of the medical oral rinse used in the study.

Design outcomes

Primary

MeasureTime frame
The intensity of postoperative mouth dryness at 2 hours after extubation;

Secondary

MeasureTime frame
Richmond Agitation-Sedation Scale (RASS) at 0, 1, 2, and 6 hours after extubation;Cough intensity score: evaluated at 0, 1, 2, and 6 hours after extubation;Adverse events;Quality of Recovery-15 score at 24 hours;

Countries

China

Contacts

Public ContactChen Wenjia

Taizhou People's Hospital

tzrmyy3367@163.com+86 139 5261 3367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026