Autism Spectrum disorder
Conditions
Interventions
Control group 2: waiting intervention group
:Treatment as usual
Intervention group:Intervention group: Dyadic Parent-Child Intervention Using Brain-Computer Interface and Artificial Intelligence (BCI-AI) Neurofeedback
Control Group 1:Control Group 1: Dyadic Parent-Child Intervention Using Brain-Computer Interface and Sham Neurofeedback
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
8 Years to 17 Years
Inclusion criteria
Inclusion criteria: 1.Inclusion criteria for children and adolescents with autism spectrum disorder: (1) Diagnose autism, Asperger's syndrome, and non-specific pervasive developmental disorder based on DSM-IV, or diagnose autism spectrum disorder based on DSM-V. The diagnosis was validated through the Autism Diagnostic Observation Scale (ADOS). (2) Passing the Wechsler Intelligence Test Fourth Edition with a total IQ greater than 70 points. Among them, the IQ for language comprehension needs to be greater than 70; (3) Age range: 8 to 17 years old; (4) Can understand Mandarin. (5) Normal or corrected visual and auditory abilities. (6) Prior to the start of the experiment, no BCI based mindfulness meditation intervention or attention training was conducted. (7) Ensure that there is a fixed parent who can participate in collaborative intervention and that the parent also meets the inclusion criteria. (8) No history of brain injury, cerebral palsy, or severe metabolic disorder; 2.Inclusion criteria for parents of children and adolescents with autism spectrum disorder who primarily care for one parent: (1) Age between 23-50 years old; (2) No head injury or surgery has been performed; (3) Can understand Mandarin. (4) Normal or corrected visual and auditory abilities. (5) Prior to the start of the experiment, no BCI based mindfulness meditation intervention or attention training was conducted. (6) Willing to participate and assist children or adolescents throughout the intervention process. (7) No history of brain injury, cerebral palsy, or severe metabolic disorders.
Exclusion criteria
Exclusion criteria: 1.Children and adolescents with autism spectrum disorder who meets the following criteria will be excluded: (1) Children or adolescents with schizophrenia, bipolar disorder, or substance dependence; (2) Children with uncontrolled epileptic seizures (>= 1 in the past 6 months) or severe self harm behavior; (3) The family will be away from Guangzhou for more than one week at the follow-up time. 2.Parents of children and adolescents with autism spectrum disorder who meets the following criteria will be excluded: (1) Parents with schizophrenia, bipolar disorder, or substance dependence; (2) Parents have uncontrolled epileptic seizures (>=1 in the past 6 months) or serious self harm behavior;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression, Anxiety and Stress Scales - 21;Score of the Quality of Life Scale for Children;Autism Spectrum Quotient; | — |
Secondary
| Measure | Time frame |
|---|---|
| Social Response Scale score;EEG indicators;Mindful Attention Awareness Scale Chid and adult version;Pittsburgh Sleep Quality Index;Parenting Stress Scale score;Emotional Expression in the Family Adjective Checklist; | — |
Countries
China
Contacts
Public ContactHuilin Zhu
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed