non-small cell lung cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 30-85 years, no contraindications for bronchoscopy surgery; 2. All patients have not undergone bronchoscopy examination before; 3. Complete clinical case information, able to be regularly admitted for efficacy evaluation; 4. Should have at least one measurable lesion.
Exclusion criteria
Exclusion criteria: 1. Tumors combined with obstructive pneumonia, bronchial asthma, tuberculosis, COPD, AIDS, diabetes, idiopathic pulmonary fibrosis, and other diseases that may affect the pulmonary microbiome characteristics; 2. Patients with a history of dust exposure or other special exposure history; 3. No use of antibiotics, corticosteroid therapy, cytokine-related drugs (such as interleukins, interferons, etc.), methotrexate, immunosuppressive cytotoxic drugs, or high-dose probiotic supplements within 3 days prior to admission; 4. Bronchoscopy examination and brushing procedures not performed under sterile conditions or contaminated specimens; 5. Incomplete clinical information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4/CD8; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary microbiota; | — |
Countries
China
Contacts
Tianjin Chest Hospital