Attention deficit hyperactivity disorder
Conditions
Interventions
Group Concetra:Take Methylphenidate Hydrochloride Extended-release Tablets (trade name: Concetra?), with a dosage of 18mg. Film
Group liyoujia:Take the sustained-release tablets of methylphenidate hydrochloride (trade name: Liyoujia?), with a dosage of 18mg per tablet.
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
7 Years to 16 Years
Inclusion criteria
Inclusion criteria: 1.The subjects are children and adolescents aged 7 to 16 years old, with no gender restrictions. 2. All patients meet the diagnostic criteria for ADHD (any subtype) according to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), confirmed through clinical history collection and structured interviews. 3. Subjects are either drug-naive or have discontinued medication for >= 6 months. For ethical reasons, individuals who previously showed no response to or could not tolerate adequate doses of methylphenidate are excluded.
Exclusion criteria
Exclusion criteria: 1) Medical contraindications for doping (such as angle-closure glaucoma, cardiovascular diseases); 2) History of epileptic seizures or abnormal EEG with epileptiform discharges; 3) Bipolar disorder, psychotic disorders, anxiety disorders, depressive disorders, tic disorders, pervasive developmental disorders; 4) Intelligence quotient (IQ) <70 as measured by the Wechsler Intelligence Scale for Children (WISC-R); 5) History of allergy to methylphenidate hydrochloride or any component of the drug; hypersensitivity to methylphenidate or previous ineffectiveness or intolerance to adequate doses of methylphenidate; history of allergy to one or more drugs, foods, etc.; 6) Subjects deemed by the investigator as unsuitable for participation in clinical trials or unable to complete the study for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total score of the Fourth Edition of the ADHD Rating Scale (SNAP-IV); | — |
Secondary
| Measure | Time frame |
|---|---|
| Weiss Functional Deficit Scale (Parent Version, WFIRS-P);BRIEF Executive Function Questionnaire Score; | — |
Countries
China
Contacts
Public Contactjinzhijuan
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed