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STROKE 120 ACTlON: a national cluster randomized controlled trial

STROKE 120 ACTlON: a national cluster randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113470
Enrollment
Unknown
Registered
2025-11-28
Start date
2025-12-10
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Control Group:Multi-measure Stroke 120 Action
Control Group:Routine health policy

Sponsors

Shanghai Minhang District Centeral Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The 2 participating community units in each region should each have a permanent population over 110,000 (people aged 60 years and above accounting for at least 15%), have similar demographic characteristics (e.g., age, gender, and education level), and have comparable local health policies (e.g., medical insurance policies, emergency system framework, stroke emergency map release, and stroke center quality control), economic levels, and public ability to recognize AIS. 2.The participating hospitals in each community unit serve >90% of AIS patients within the community unit, have a well-established stroke center, and have comparable standardized treatment capabilities for AIS (including 4.5-hour hospital arrival rate of AIS, rate of using 120 emergency ambulances after AIS, and rate of IVT after AIS). 3.The participating communities are capable of implementing STROKE 120 multifaceted intervention campaign within its community unit. 4.To avoid cross-contamination, the physical distance between any two community units exceeds 20 kilometers.

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

MeasureTime frame
Arriving hospital within 4.5 hours after symptom onset among incident acute ischemic stroke cases within participating community units;

Secondary

MeasureTime frame
Intravenous thrombolysis after acute ischemic stroke;Total hospitalization costs;All-cause mortality within 3 months after acute ischemic stroke;Out-of-pocket hospitalization costs;Time from onset to action after acute ischemic stroke;Time from onset to hospital admission after acute ischemic stroke;Use of 120 emergency ambulances after acute ischemic stroke;Mechanical thrombectomy after acute ischemic stroke;Ordinal 7-level modified Rankin Scale score at 3 months after acute ischemic stroke;Composite outcome of death or major disability at 3 months after acute ischemic stroke;

Countries

China

Contacts

Public ContactJing Zhao

Shanghai Minhang District Centeral Hospital

zhaojingssmu@163.com+86 21 64923400

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026