non-small cell lung cancer
Conditions
Interventions
Case series:None
Sponsors
Zhongshan Hospital Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Consistent with the "Chinese Medical Association Guidelines for the Diagnosis and Treatment of Lung Cancer (2018 Edition)," histologically confirmed as NSCLC; 2. According to the 8th edition of the AJCC TNM staging system, it is stage III B to IV and not suitable for surgery; 3. Age >=18 years; 4. First-time recipients of immunotherapy combined with chemotherapy; 5. Baseline data within 1 month before the start of treatment is complete (at least including chest CT, pulmonary function, and laboratory tests); 6. At least 1 measurable lesion according to RECIST 1.1; 7. Receiving immune checkpoint inhibitor therapy for more than 2 cycles; 8. Clinical data is complete.
Exclusion criteria
Exclusion criteria: 1. Presence of other malignant tumors; 2. Previous exposure to immunotherapy or systemic chemotherapy; 3. Patients with severe dysfunction of vital organs (heart, liver, lungs, kidneys) and bone marrow at baseline; 4. Presence of severe infectious diseases, active autoimmune diseases, or immune deficiencies that significantly affect immune function; 5. Organ transplantation; 6. Pregnant or lactating women; 7. Incomplete clinical treatment or follow-up information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival (PFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| The disease control rate (DCR); | — |
Countries
China
Contacts
Public ContactXu Nuo
Zhongshan Hospital Fudan University
Outcome results
None listed