Lumbar instability, discogenic low back pain, lumbar spondylolisthesis, lumbar spinal stenosis, etc.
Conditions
Interventions
Control group:Use non-absorbable bone wax
Experimental group:Use absorbable bone wax
Sponsors
Shanghai Tongren Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients are between 18 and 75 years old, regardless of sex. 2. Lumbar instability, discogenic low back pain, lumbar spondylolisthesis, lumbar spinal stenosis and other patients who plan to receive oblique lateral lumbar interbody fusion. 3. Subjects can understand the purpose of the experiment and voluntarily participate in and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with hemorrhagic diathesis or coagulation disorders (prothrombin time [PT] >=18 s); those on long-term anticoagulant therapy. 2. Patients with lumbar infection or fracture. 3. Patients allergic to polyethylene glycol, sodium carboxymethylcellulose, or bone wax (including beeswax, paraffin, and isopropyl palmitate). 4. The patient is in critical condition, and it is difficult to make an exact evaluation of the effectiveness and safety of the instrument. 5. The researcher judged that the patient's compliance was poor and the study could not be completed as required. 6. Pregnant or pregnant women in the past year, lactating women. 7. Patients with major complications or comorbidities, including severe cardiac, hepatic, or renal disease, or other chronic conditions that may affect surgical risk or study outcomes. 8. Patients with an investigator-estimated survival of less than six months. 9. Patients with severe osteoporosis (bone mineral density T-score <= -2.5 accompanied by fragility fractures).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fusion rate at 6 months postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Successful hemostasis rate;Assessment of wound drainage volume and presence of bloody exudate on the first postoperative day; | — |
Countries
China
Contacts
Public ContactXiaojian Ye
Shanghai Tongren Hospital
Outcome results
None listed