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Application of Transcutaneous Auricular Vagus Nerve Stimulation with Different Frequencies in Monitored Anesthesia Care for Percutaneous Endoscopic Lumbar Discectomy

Application of Transcutaneous Auricular Vagus Nerve Stimulation with Different Frequencies in Monitored Anesthesia Care for Percutaneous Endoscopic Lumbar Discectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500113351
Enrollment
Unknown
Registered
2025-11-27
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar disc herniation

Interventions

Group 30Hz:Continuous electrical stimulation at a frequency of 30Hz
Group 1Hz:Continuous electrical stimulation at a frequency of 1 Hz
Group 10Hz:Continuous electrical stimulation at a frequency of 10Hz
Control Group:No stimulation

Sponsors

Hebei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Surgical patients (male or female) who undergo percutaneous endoscopic lumbar discectomy under monitored ;anesthesia care at Hebei Provincial People's Hospital; 2.Aged 18 to 65 years old; 3.With clear consciousness and capacity for civil conduct; 4.Without surgical or anesthetic contraindications;

Exclusion criteria

Exclusion criteria: 1.Patients with severe respiratory depression; 2.Patients with known or suspected gastrointestinal obstruction, including paralytic ileus; 3.Patients with severe arrhythmia; 4.Patients with severe hepatic insufficiency; 5.Patients who refuse; 6.Patients in whom severe adverse reactions occur during surgery, leading to surgical termination or changes in anesthesia method; 7.With epilepsy, a history of epilepsy, or other neurological diseases; 8.Patients with known allergy to oliceridine; 9.Patients with infection or damage to the skin at the stimulation site;

Design outcomes

Primary

MeasureTime frame
VAS;MOAA/S;

Secondary

MeasureTime frame
Additional dose of oliceridine fumarate;Spo2;Surgeon Satisfaction;Patient Satisfaction;HR;HRV;Blood Pressure;

Countries

China

Contacts

Public ContactZhang Dong

Hebei General Hospital

zhangdongdoctor@126.com+86 311 8598 8127

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026