Cirrhosis
Conditions
Interventions
Observation Group of Liver Cirrhosis (Retrospective part):None
Observation Group of Liver Cirrhosis (Prospective part:None
Sponsors
Sir Run Run Shaw Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Retrospective section 1. Patients with liver cirrhosis Aged 18 to 75. (2) Liver cirrhosis is clinically diagnosed and there is no HCC. (3) No malignant tumors have been suffered within the past five years. (4) The Child Pugh classification is either A or B. (5) The clinical information such as AFP, liver ultrasound and/or imaging, and high-risk factors for HCC is complete. 2. HCC patients with liver cirrhosis: Aged 18 to 75. (2) The diagnosis of HCC and liver cirrhosis is in line with clinical guidelines. (3) No other cancers have been suffered. (4) Exclude malignant tumors in other parts. (5) The clinical information such as AFP, liver ultrasound and/or imaging, high-risk factors for HCC and HCC staging is complete. 3. Healthy individuals Aged 18 to 75. (2) No liver diseases, such as liver cancer, liver cirrhosis, hepatitis, intrahepatic bile duct stones, etc. (3) No malignant tumors have been suffered within the past five years. Forward-looking section Aged 18 to 75. 2. Patients with liver cirrhosis who have not yet been diagnosed with HCC. 3. No malignant tumors have been suffered within the past five years. 4. The Child Pugh classification is either A or B. 5. Voluntarily participate in this study and sign the informed consent form. If the subject is unable to read and sign the informed consent form due to reasons such as incapacity for civil conduct, the informed consent form must be signed by their guardian on their behalf during the informed process.
Exclusion criteria
Exclusion criteria: Retrospective section 1. Those with incomplete clinical data. 2. Clinical samples that do not meet the research requirements. Forward-looking section 1.Patients with liver cirrhosis caused by circulatory disorders, drug or toxic substances, or parasitic infections. 2. Vulnerable groups other than the elderly, including those with mental illness, cognitive impairment, critically ill patients, pregnant women, illiterates, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine examination;Blood biochemistry examination;B-ultrasonography; | — |
Countries
China
Contacts
Public ContactLiang Xiao
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed