Degenerative lumbar spinal stenosis
Conditions
Interventions
NSAIDs group:None
Limaprost Tablets group:None
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Diagnosed with degenerative lumbar spinal stenosis (DLSS), regardless of gender; 2. Negative straight leg raise test; 3. Presence of lower extremity symptoms such as numbness, pain, and weakness; 4. Patients who have started receiving treatment for DLSS with non-steroidal anti-inflammatory drugs (NSAIDs) or a combination of NSAIDs and limaprost tablets (as determined by the investigating physician); 5. Voluntarily sign the informed consent form and be willing to receive standardized pharmacotherapy;
Exclusion criteria
Exclusion criteria: 1. Subjects with contraindications to limaprost tablets; 2. Subjects who received limaprost tablet treatment within 12 weeks prior to the baseline visit; 3. Subjects who are pregnant or lactating; 4. Subjects diagnosed with lumbar disc herniation; 5. Subjects who are currently participating in other interventional clinical studies or plan to participate in other interventional clinical studies within the 3-month observation period; 6. Subjects deemed by the investigator to have poor compliance or who may not be able to complete data collection; 7. Subjects with any disease that the investigator deems may interfere with their participation in this study, such as diseases requiring emergency surgery, severe cognitive impairment, or other comorbidities that are expected to affect the subjects' ability to fully complete visit and assessment schedules.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain (low back pain, lower extremity pain);EQ-5D,ODI,JOA;Change in walking distance from baseline;Low back pain, lower limb pain, lower limb numbness, resting pain, movement-related pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events;Changes in healthcare resource utilization (HCRU) from baseline;Surgical treatment situation; | — |
Countries
China
Contacts
Public ContactYu Zhang
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed