Ovarian cysts are common tumors of the female reproductive system, predominantly affecting women aged 20 to 50. Laparoscopic ovarian cystectomy, with its advantages of minimal trauma, reduced bleeding, and quicker postoperative recovery, has gradually replaced open surgery. However, the establishment of a carbon dioxide pneumoperitoneum during laparoscopic surgery can impact the patient's respirat
Conditions
Interventions
Group C:Propofol 5.0mg/ (kg·h) + remifentanil 0.1µg/ (kg·h)
Group R1:Remimazolam 1.0mg/ (kg·h) + remifentanil 0.1µg/ (kg·h)
Group R2:Remimazolam 1.5mg/ (kg·h) + remifentanil 0.1µg/ (kg·h)
Group R3:Remimazolam 2.0mg/ (kg·h) + remifentanil 0.1µg/ (kg·h)
Sponsors
Ji 'an Central People's Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for the indications of laparoscopic ovarian cystectomy as stipulated in the "Modern Hospital Diagnosis and Treatment Routine (Surgery and Obstetrics and Gynecology Volume)" and be confirmed by imaging examinations; ASA grade I or II, aged 20 to 45 years old, body mass index (BMI) 18 to 28 kg/m^2; 3. Meet the indications for anesthesia; 4. Estimated operation time: no more than 2 hours; 5. Mentally normal and willing to cooperate with the research
Exclusion criteria
Exclusion criteria: 1.May present with suspected difficult airway or obesity; 2.History of alcohol dependence or drug dependence; 3.History of allergy to the anesthetic drugs used in this study; 4.Abnormal function of major organs such as the heart, liver, and kidneys; 5.History of recent upper respiratory tract infection; 6.Pregnant or lactating women;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heart rate;Oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical duration, time to loss of eyelash reflex, and time for the Bispectral Index (BIS) to drop below 60 during anesthesia induction are measured to evaluate the anesthetic efficacy.;The number of times propofol and remimazolam need to be supplemented during the surgery;Adverse reactions;During the recovery of anesthesia and SAS; | — |
Countries
China
Contacts
Public ContactGuo Genhua
Ji 'an Central People's Hospital
Outcome results
None listed