Ocular Surface Damage
Conditions
Interventions
Group 2: Age- and sex-matched healthy controls:N/A
Group 1: Abusive drug users :N/A
Sponsors
Department of Ophthalmology and Visual Sciences (DOVS), Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
15 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 15 years old and above; 2. Able to provide informed consent; 3. For healthy controls: no history of neurological or severe medical diseases, substance abuse or mental disorders.
Exclusion criteria
Exclusion criteria: 1. Unable to provide valid written consent; 2. Pregnant, considering becoming pregnant, or lactating; 3. Significant medical co-morbidities; 4. Mental retardation; 5. Known posterior segment pathology (e.g., diabetic retinopathy, age-related macular degeneration).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To report the ocular surface symptoms and signs and to examine the tear film and meibomian gland biomarkers in addictive substance users.; | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate the severity and nature of ocular findings with substance type, duration of use, and abstinence, and are further associated with specific clinical and behavioral characteristics of the users.; | — |
Countries
China
Contacts
Public ContactCHONG Kam Lung Kelvin
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong
Outcome results
None listed