None
Conditions
Interventions
Experimental group:A volume of 4 Units (400 mL) of high-hematocrit apheresis group O red blood cells will be collected. The procedure will be performed in strict accordance with the standard operating
Sponsors
The Fourth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. We plan to recruit 10 individuals aged between 18 and 55, male, with a body weight of over 70 kg, blood type O, and peripheral hemoglobin (Hb) level of >= 150 g/L. 2. They must pass the routine physical examination and meet the national blood donation standards. 3. There are no abnormalities in the blood donation health inquiry, MMSE questionnaire survey, and SF-36 brief health questionnaire.
Exclusion criteria
Exclusion criteria: 1. Abnormal or suppressed hematopoietic function of the bone marrow; 2. Presence of fever or infectious diseases; 3. Taking drugs that inhibit compensatory cardiovascular responses, such as beta-blockers; 4. Taking drugs that promote or inhibit hematopoietic function; 5. Having a blood donation history within the past six months or other situations that do not meet the national blood donation standards.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Titer of IgM anti-A/B antibodies;Titer of IgG anti-A/B antibodies;Weight of Blood;Free hemoglobin;Coomb's;Residual Plasma Volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin;Red blood cell count, RBC;Hematocrit;Ferritin; | — |
Countries
China
Contacts
Public ContactChen Guanyi
The Fourth Medical Center of PLA General Hospital
Outcome results
None listed